Product RED Art Auction Raises $42.6M For Global Fund Programs In Africa

Irish musician and advocate Bono and British artist Damien Hirst on Thursday raised about $42.6 million at the Product RED art auction in New York City to benefit HIV/AIDS, tuberculosis and malaria programs in Africa, Reuters reports. The RED Auction included 83 red-themed works of contemporary art donated by several artists (Michaud, Reuters, 2/15). The proceeds will go to the United Nations Foundation to support Global Fund To Fight AIDS, Tuberculosis and Malaria programs.

The auction raised significantly more than the upper pre-sale estimate of $29 million, AFP/Google reports. Artists who contributed their work included Georg Baselitz, Howard Hodgkin, Jasper Johns, Anish Kapoor and Jeff Koons. Hirst sold seven pieces for more than $19 million (AFP/Google, 2/15).

“Tonight we got serious about love, and not just the love of art, but the love of our brothers and sisters suffering from AIDS in the poorest places on the planet,” Bono said in a release from Sotheby’s auction house in New York. Sotheby’s organized the auction (AP/Google, 2/15). The auction brought the total amount raised by RED to more than $100 million since it was launched (AFP/Google, 2/15).

Reprinted with kind permission from kaisernetwork. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at kaisernetwork/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork, a free service of The Henry J. Kaiser Family Foundation© 2005 Advisory Board Company and Kaiser Family Foundation. All rights reserved.

NFL Players in Indonesia to Support WFP and Help Tsunami Survivors

BANDA ACEH – Two of the National Football League’s (NFL) top players, New York Giants’ quarterback Kurt Warner and wide
receiver Amani Toomer, have arrived in Indonesia to assist the victims of the tsunami and support the United Nations World
Food Program (WFP) in its efforts to deliver food to survivors.

The purpose of their visit is to raise awareness about the critical work WFP is doing in Asia, where the food aid agency is
assisting more than a million tsunami survivors. Last month, WFP provided over 7,000 metric tons of food commodities to
assist over 400,000 people in Indonesia alone. In February, more than 500,000 people will be assisted with rice, fortified
noodles, biscuits, canned fish and vegetable oil.

Both Warner and Toomer and their wives, Brenda and Yola respectively, had canceled their previous holiday plans to devote
themselves to a humanitarian cause. The two couples arrived in Indonesia on February 11 and departed today for the city of
Banda Aceh, which was devastated by the December 26 earthquake and tsunami.

While living with other UN humanitarian workers in the tented UN compound in Banda Aceh, they will work on the frontlines of
WFP’s emergency operation, which will include loading a helicopter with food and participating in food distributions to
displaced families in Banda Aceh and in the devastated coastal town of Lamno.

In addition, they will help clean the rubble in a secondary school in Banda Aceh, as well as meet with the provincial soccer
team, which lost a number of its key players in the disaster.

“In many of our operations, WFP works with respected public figures to help tell the story of WFP’s work. It is particularly
important for the victims of the tsunami and their tragedy, which is receiving worldwide attention,” said Mohamed Saleheen,
WFP’s country director in Indonesia.

Their itinerary will also include a courtesy visit to the USS Mercy, a US Navy hospital ship which is operating offshore
along Indonesia’s west coast. The US military, along with militaries from around the world, played a vital role in delivering
significant amounts of food in the first phase of the emergency operation.

When the visit ends on February 16, the Toomers will continue on to Sri Lanka to help in reconstruction activities. They will
be joined there by Kansas City chiefs full back Tony Richardson. Currently, WFP is helping to feed more than 850,000 people
in Sri Lanka, with a large logistics network spread throughout the country.

“The fact that the NFL players are involved demonstrates their commitment and sympathy to the victims of this huge natural
disaster. On behalf of the people we serve, we are very grateful to host them as part of the WFP team. Teamwork is the key to
our success,” added Saleheen.

NFL players have been active with the WFP throughout the tsunami crisis. The Indianapolis Colts donated $50,000 and a further
$60,000 was raised by fans at a match between the Colts and the Denver Broncos on January 9. Quarterbacks Peyton Manning and
Donovan McNabb volunteered their time to record a Public Service Announcement for WFP, which aired during NFL playoff games
in January. The PSA was shown during five playoff games, with the airtime, valued at millions of dollars, donated by the NFL.

WFP is the world’s largest humanitarian agency: we give food aid to an average of 90 million people in more than 80
countries each year, including 56 million hungry children.

WFP Global School Feeding Campaign – For just 19 US cents a day, you can help WFP give children in poor countries a healthy
meal at school – a gift of hope for a brighter future.

Visit the website: wfp.

For more information please contact (email: firstname.lastnamewfp):

Heather Hill,
Mob:+66 17019208

Inigo Alvarez,
Mob: + 62 811864415

Mia Turner,

Mob: +62 811864383

Caroline Hurford,
Tel: + 39 06 65132330,
Mob: + 39 3481325018

Trevor Rowe,
WFP/New York,
Mob: +1 646 8241112,
Tel: +1 212 9635196

Jennifer Parmelee,
Tel: +1 2026530010 ext 1149,
Mob: +1 2024223383

Christiane Berthiaume,
Tel: + 41 229178564.
Mob: + 41 792857304

Factors In Delaying Or Declining Total Knee Replacement Surgery

A study led by Dr. Ann F. Jacobson, associate professor in Kent State’s College of Nursing, unveils the reasons why people may initially choose to postpone but ultimately undergo total knee replacement surgery and emphasizes the need for better patient education before and after the procedure.

Patients need more education and support about total knee replacement and making the decision to have it, and there is still a need for investigation into new and better ways to provide these, Jacobson says.

“This study sought to better understand patients’ pre-and post operative experiences with total knee replacement surgery,” says Jacobson. “These patients’ perspectives have rarely been the topic of research yet numerous existing studies of total joint replacement of the hip or knee indicate that eligible patients delay or decline the procedure for reasons that haven’t been well understood.”

The Four Themes of Patient Experience

Study results identified four overarching themes in patients’ experiences of total knee replacement, which the researchers named “putting up and putting off,” “waiting and worrying,” “letting go and letting in,” and “hurting and hoping.”

A participant described “putting up and putting off” as, “I’m tired of it. I am a very active person.” Another explained “putting off” the decision to have total knee replacement as, “you just keep hoping it will get better.”

The “waiting and worrying” stage begins after deciding to undergo surgery. One person said “I put this off for years. I can’t wait to get it over with.” This period involves worrying that “something can go wrong.”

The experience of “letting go and letting in” was described as “I had to accept the loss of control” and independence and “letting in” by accepting help and encouragement. One aspect of encouragement was hearing from others who had successful total knee replacement outcomes.

The “hurting and hoping” aspect of the experience was pervaded by pain: “The pain is the main thing with the knee,” but also by hope: “Gotta keep your eye on the prize.”

Patients yearned for a return to being a “normal human being,” doing such everyday things as housework, walking the dog, or gardening, with ease and comfort.

Source: Rachel Wenger-Pelosi

Kent State University

Humanitarian Aid Reaches Over 10,000 HIV Affected Orphans In Lilongwe, Malawi

(OTC Bulletin Board: NTRZ) announced that this week they began distributing
80,000 pounds of their RiSolubles(R) product to thousands of orphans
through Community Based Organizations in Malawi as part of an extraordinary
collaborative effort with Feed the Children, Raising Malawi, an
organization supported by Madonna, and The Malaria Solution Foundation. The
NutraCea Feeding Program team headed by NutraCea Senior Executives, Margie
Adelman and Kody Newland were in Malawi seeing first hand the drastic
situation that the country is facing.

“Raising Malawi is a humanitarian aid project supported by Madonna and
Michael Berg. Our mission is to provide direct physical assistance,
long-term sustainability and psycho-social support to many of Malawi’s two
million orphans and vulnerable children. Thanks to Feed the Children,
NutraCea and the Malawian Government, approximately five thousand children
at the Consol Homes-Raising Malawi Orphan Care Center will receive improved
nutrition. The health progress will be monitored and documented to track
the benefits of this nutritional supplement for children- especially those
infected with HIV,” said Philippe van den Bossche, Executive Director of
Raising Malawi.

“The situation in Malawi is desperate,” said Larry Jones, president and
co-founder of Feed the Children. “Malawi has a population of 12 million
people, roughly the same as the state of Illinois. Something that people in
America cannot believe is that of the entire population of Malawi, one
million are orphaned children. This harsh statistic means one thing — we
all must do something to help. We thank NutraCea for being so committed to
a socially conscious effort that will change the lives of thousands of
children in Malawi and we’re happy to collaborate with them.”

The distribution efforts are being supported by the First Lady of
Malawi, Ethel Mutharika and the Ethel Mutharika Foundation. Paradiso House,
in Lilongwe was a recipient of the first shipment together with the
Mtsiliza Community, Feed the Children orphanage and Consol Homes, Raising
Malawi Orphan Care Center. According to Member of Parliament, Nancy Tembo
who was one of the honored guests at the Paradiso House, “By bringing food
directly to the children, NutraCea is making a real difference —
grassroots efforts of this nature are exactly what’s needed here.” The
First Lady’s daughter Duwa Mutharika Kafoteka was representing her mother
and Founder of the Ethel Mutharika Foundation and she thanked NutraCea for
their efforts to help feed orphaned children in Malawi. Mutharika said, “We
look forward to expanding this feeding program in Malawi and we are
grateful to all the groups, especially NutraCea, who have come together to
bring this much needed humanitarian aid to our country.”

The initial product distribution was made possible through funding
raised by The Malaria Solution Foundation with a purchase of 40,000 pounds
of NutraCea’s RiSolubles. This donation was matched in kind with an
additional 40,000 pounds from NutraCea for a total of 80,000 pounds, which
will feed approximately 10,000 children for almost ten months.

“Our RiSolubles is a very beneficial food supplement for these
malnourished children,” said Margie Adelman, Senior Vice President of
NutraCea. “It’s made from the highly nutritious soluble fraction of our
proprietary stabilized rice bran that can be easily mixed with water and
consumed. Even in serious stages of malnutrition, the children benefit from
the rich bounty of protein, carbohydrates, healthy fats and a wide range of
vitamins and minerals because the product is easily digested.”

“We’re delighted to help raise the funding necessary for this project,”
said James Christiansen, President and CEO of The Malaria Solution
Foundation. “The experience we have in Africa combined with help we receive
from companies like NutraCea is a chance to help hundreds of thousands of
malnourished children. Any amount of assistance we can provide is a step
toward ending world hunger and we’re currently working on expanding this
program with NutraCea into other countries in Africa.”

“Despite all the well meaning efforts underway to solve our world
hunger issues, we still have a very long way to go. However, if it were
possible to collect even a small portion of the 60 million metric tons of
rice bran that are discarded annually, this extraordinary technology could
convert enough stabilized rice bran into RiSolubles to make a meaningful
impact on the close to one billion people that suffer from hunger and
malnutrition throughout the world,” said Kody Newland, Senior V.P. Sales,

“We are very grateful to Feed the Children, Raising Malawi and The
Malaria Solution Foundation for collaborating on this project to benefit
the orphans of Malawi, as well as The First Lady of Malawi, Ethel Mutharika
and His Excellency Alan Eastman the US Ambassador to Malawi. It’s only by a
substantial collaborative effort that we were able to bring this to the
children before the holidays,” added Adelman. “Not only are we going to
help feed children through the distribution of our RiSolubles nutritional
beverage, but with the help of Raising Malawi, we intend to track the
progress of the children’s overall health as they continue to consume the
RiSolubles during the next ten months. NutraCea’s RiSolubles has been shown
to help reverse malnutrition in feeding programs conducted in other
countries. The program in Malawi is part of an on-going commitment by
NutraCea to help eradicate world hunger,” Adelman said.

For more information about the organizations listed above, please visit
the following web sites:




To watch video on this story, go to:

About NutraCea

NutraCea is a world leader in production and utilization of stabilized
rice bran. They hold many patents for stabilized rice bran production
technology and proprietary nutraceutical formulas ranging from arthritis,
chronic bowel conditions, and effective diabetes control to cardiovascular
disease treatment protocols. NutraCea’s proprietary technology enables the
creation of food and nutrition products to be unlocked from rice bran,
normally a waste by-product of standard rice processing. Committed to
helping the under fed, they’re heavily involved in providing product and
technology for developing countries through NutraCea’s RiceAde feeding
program. More information can be found in the Company’s filings with the
SEC and you can visit the NutraCea web site NutraCea.

Forward Looking Statements

This release contains forward-looking statements. Actual results may
differ from those projected due to a number of risks and uncertainties,
including, but not limited to the possibility that some or all of the
pending matters considered by the Company may not proceed as contemplated
and the matters specified in the Company’s filings with the Securities and
Exchange Commission. These statements are made based upon current
expectations that are subject to risk and uncertainty. The Company does not
undertake to update forward-looking statements in this news release to
reflect actual results, changes in assumptions or changes in other factors
affecting such forward- looking information. Assumptions and other
information that could cause results to differ from those set forth in the
forward-looking information can be found in the Company’s filings with the
Securities and Exchange Commission, including the company’s most recent
periodic report.


Japan’s Nuclear Crisis Could Create Serious Health Problems

Japan’s nuclear power plant crisis could create serious health problems if too much radiation is released into the atmosphere. Reactor problems at Japan’s Fukushima Daiichi Nuclear Power Plant could lead to exposure to large amounts of radioactivity, which can be lethal to humans and has long-term health consequences.

Radioactive substances are dangerous because they are unstable molecules that are continually exploding. When they explode, they emit ionizing radiation containing a high amount of energy. When particles emitted from an exploding molecule hit a cell in the body, considerable damage ensues. Ionizing radiation is like a fusillade of miniature bullets hitting the body or miniature bombs that explode within cells.

There are two types of radioactive exposure:

1) Acute exposure to ionizing radiation. Particles, or energy waves emanating from the radioactive source, can penetrate the body and damage vital cellular machinery. The greatest concern is when it damages DNA, preventing it from making new proteins to keep the cell alive. Worse yet, it may begin to copy itself abnormally turning the cell into a cancer cell.

2) Chronic exposure arising from ingestion or inhalation of the radioactive material. Radioactive materials are released as gases or small particulates. The gases can be inhaled and absorbed into the body through the lungs. Particulates are also dispersed into the air and can also be inhaled. The particulate will ultimately settle on the ground, contaminating everything it contacts. It’s incorporated into plants growing on the contaminated ground, entering the food chain. This results in long-term sustained exposure to the radioactive molecules. Inside the body, the radioactive molecules continue to explode, damaging the cells in which they are located.

There are four types of radioactive materials (radioiosotopes) generally released during a nuclear meltdown.

Tritium (hydrogen-3) and nitrogen-16 are of moderate concern. The radioactive particles released from tritium travel less than a thousandth of an inch and have such low energy, they cannot penetrate skin. There is some danger from inhaled tritium because cells containing exploding tritium molecules can be damaged. Ingested tritium is eliminated from the body fairly rapidly.

Nitrogen-16 has a short half-life of 7 seconds. Within one minute of formation, less than 1 percent of it remains radioactive. However, it emits very high energy gamma radiation waves. The concern for exposure to nitrogen-16 is primarily to individuals very close to the site at which the nitrogen-16 is formed.

The greatest danger comes from cesium-137 and iodine-131. These radioisotopes emit relatively large amounts of energy. Cesium-137 has a half-life of 30.1 years, so it takes 200 years to decrease to 1 percent of its radioactivity. When inhaled or ingested, it mimics potassium, accumulates in muscle, and damages cells, especially their DNA. Damage to DNA is a leading cause of cancer.

Iodine-131 mimics non-radioactive iodine and accumulates in the thyroid gland. Iodine-131 has a half-life in the body of 7.6 days. The thyroid uses iodine to make thyroid hormone, which is critical for control of cellular metabolism. Iodine-131 accumulation in the thyroid gland can cause thyroid cancer. At excessive levels, it destroys the thyroid gland. Thyroid function is extremely important in infants because thyroid hormone is critical for brain development. Thyroid hormone deficiency causes cretinism, a disease associated with mental retardation and physical impairments.

Robert C. Speth, Ph.D., is a professor of pharmaceutical sciences at Nova Southeastern University’s College of Pharmacy.

Nova Southeastern University

Alzheimer’s Society And BBC Launch Brain Training Trial With A ‘Bang’

Alzheimer’s Society has teamed up with the BBC’s Lab UK to launch Brain Test Britain, a unique trial that will seek an answer to the question: Does brain training really work?

Launching on BBC One tonight (1930, Monday, 7 September 2009), Brain Test Britain will investigate the effects of brain training on mental fitness. Initial results will be announced in a Bang Goes the Theory special, early next year. The experiment will continue for a further nine months looking closely at whether brain training can maintain or even improve the brain. Alzheimer’s Society hopes results will be a step towards solving whether brain training can reduce the risk of dementia.

Celebrities and BBC presenters will be pitched against each other as they get ‘brain fit’. Supporters include BBC One’s Evan Davis and Alzheimer’s Society ambassadors Richard McCourt of Dick and Dom, Tania Bryer and Russell Grant.

Richard McCourt of Dick and Dom, Alzheimer’s Society Ambassador says,
‘I always wondered if any of these brain training gadgets and games really work. I’m looking forward to being trained up and finding out a lot more about how our brains function. The more we know about the brain, the nearer we’ll come to finding a cure for dementia – and that’s the reason why I want to be involved.’

Professor Clive Ballard, Director of Research, Alzheimer’s Society says,
‘Every week thousands of people spend time exercising their brain using some form of computer-based brain training, but the jury’s still out on whether exercising your brain can boost your brain power. As Brain Test Britain asks the question, everyone can help with the answer. With one million people set to develop dementia in the next 10 years, it’s vital we understand the truth behind the old saying use it or lose it. Join us today and have fun while helping to solve one of the biggest mysteries of the brain. Does brain training really work?’

Brain Test Britain will be powered by Lab UK, a BBC website that enables the public to participate in groundbreaking scientific experiments online. Volunteers are being asked to train their brains for 10 minutes at a time, three times a week, for at least six weeks. A one-off ‘Bang Goes The Theory’ special will reveal the results of the Brain Test Britain experiment early next year. Alzheimer’s Society advises that leading a healthy lifestyle is the best way to reduce your risk of dementia. The best evidence is to eat a healthy diet, keep active, don’t smoke, get blood pressure and cholesterol checked and keep a healthy weight.

Alzheimer’s Society

Asthma May Be Overdiagnosed In Obese Patients

A new study reveals that, despite lack of evidence, obese patients are often diagnosed with asthma. Researchers at Newark Beth Israel Medical Center in New Jersey studied 20 patients, all of whom had a diagnosis of asthma, but none of whom exhibited any spirometric evidence of airway obstruction. The body mass index (BMI) was calculated, and bronchoprovocations tests were performed. In all, 90 percent of patients had an above-normal BMI. Of that, 61 percent were nonreactive to methacholine, suggesting an overdiagnosis of asthma in obese patients. Researchers suggest bronchoprovocation testing should be considered in such patients.

CHEST 2006 abstract briefs

Contact: Jennifer Stawarz

American College of Chest Physicians

Alzheimer’s Society Responds To Health Select Committee Inquiry On NICE, UK

People in the early stages of Alzheimer’s disease should never have been denied drug treatments the Alzheimer’s Society said.

This announcement comes as a Health Select Committee inquiry criticised the National Institute for Health and Clinical Excellence’s (NICE) narrow remit and structure.

Neil Hunt chief executive of the Alzheimer’s Society says,

‘Today’s report confirms that people with Alzheimer’s disease should not have been denied access to drugs. This is a victory for common sense. It is good news for patients. We hope the Department of Health will implement the suggested reforms. This will reduce the number of challenges against NICE, such as ours on Alzheimer’s drugs, and enable it to regain the public confidence it has lost.’

Importantly the Health Committee highlighted that NICE’s economic evaluations do not adequately take into account the wider benefits of treatment to society, including the benefit to carers.

Neil Hunt continues,

‘For years the Alzheimer’s Society has campaigned to have the benefits that drug treatments bring to carers sufficiently recognised by NICE. We hope changes will be made immediately to address this important issue.’


- In March 2005, NICE, the government body which produces guidance on which drug treatments should be funded by the NHS, ruled four drug treatments licensed for Alzheimer’s disease (Aricept, Exelon, Reminyl and Ebixa) should no longer be funded by the NHS. It acknowledged that the drugs were clinically effective, but stated that they were not cost effective. Following an unprecedented response NICE changed its position to allow only people only in the moderate stages of the disease access to drug treatments. Following an unsuccessful appeal to an internal review body the Alzheimer’s Society challenged the decision in the high court.

- Pfizer/Eisai, manufacturer of Aricept, was the lead claimant in this judicial review. The Alzheimer’s Society acted as one of a number of separate interested parties in this challenge. Its legal team represented the interests of people with dementia and their carers and raised additional arguments.

- The Alzheimer’s Society does not accept funding or any other support from the pharmaceutical industry for its campaign on access to Alzheimer’s drug treatments. Click here for details of the Alzheimer’s Society pharmaceutical policy.

- Further information about the campaign can be viewed here.

- Nice guidance applies to England and Wales. People currently on the drug treatments will continue to receive them.

- 1 in 3 older people will end their lives with a form of dementia

- 700,000 people in the UK have a form of dementia, more than half have Alzheimer’s disease. In less than 20 years nearly a million people will be living with dementia. This will soar to 1.7 million people by 2051. 1 in 6 people over 80 have dementia.

- The Alzheimer’s Society champions the rights of people living with dementia and those who care for them. The Alzheimer’s Society works in England, Wales and Northern Ireland

- As a charity, the Alzheimer’s Society depends on the generosity of the public to help it care, research and campaign for people with dementia. You can donate now by calling 0845 306 0898 or visiting alzheimers

- The Alzheimer’s Society helpline number is 0845 300 0336 or visit alzheimers

View drug information on ARICEPT; Exelon; Reminyl.

Future Secured For World-Class Asthma Research Centre, UK

The future of the world-class MRC-Asthma UK Centre in Allergic Mechanisms of Asthma in London has been secured for a further five years, thanks to renewed commitment from the Medical Research Council (MRC). This will allow the centre to build upon the many important scientific and medical advances which it has already made by continuing its research to better understand asthma and develop new ways of preventing and treating the condition.

The MRC-Asthma UK centre is dedicated to improving the health of the 5.4 million people in the UK with asthma. Founded in 2005, it brings together over 200 doctors and scientists from a wide range of backgrounds and with diverse expertise. This enables a faster pace of research and ensures that new discoveries and treatments are put to use as quickly as possible. This renewed funding will not only help to support academics who are currently carrying out vital research but will also assist in training the next generation of scientists and doctors specialising in asthma and allergy.

Since its inauguration, the MRC-Asthma UK centre has developed an outstanding reputation for its translational, multi-disciplinary approach. All of this has been made possible through a series of unique partnerships between Imperial College London, King’s College London, their respective NHS partners, the MRC and Asthma UK.

When reviewing the Centre’s progress, the Centre’s International Advisory Board commented that it was impressed by the Centre. It highlighted that it was flourishing, had developed a remarkably collaborative structure, and had been successful in publishing high-quality, peer-reviewed publications that have made a major impact in this area of research.

Leanne Metcalf, Director of Research for Asthma UK commented: ‘The MRC-Asthma UK Centre plays a vital role in advancing our understanding of asthma and allergies. We are committed to the Centre’s success and the MRC’s renewed investment is a huge boost to the Centre’s ongoing work to develop new ways of preventing and treating the condition.’

Professor Tak Lee, Head of the Centre at King’s College London, said: ‘I am absolutely delighted that our Centre has received approval from the MRC for another five years of continued funding, especially as the current financial climate is so tight.

‘Over the last five years we have made a number of important discoveries which we hope will translate into patient benefit. This couldn’t have been achieved without the supportive infrastructure and vision of our funders, host institutions and our other partners. The Centre is an excellent example of what can be accomplished when outstanding colleagues across institutions bring complementary strengths and work together for the benefit of people with asthma.’


Asthma UK

Broncus Introduces Innovative Bronchoscopic Tools To Be Used In The Diagnosis And Treatment Of Lung Diseases

Broncus Technologies, Inc., a medical device company focused on developing minimally-invasive innovations for lung diseases, announced today at the International Conference of the American Thoracic Society (ATS) the release of its first commercial products: the LungPoint™ Virtual Bronchoscopic Navigation and Treatment Planning System, Yield™ Mini Doppler Probe, and Yield™ Transbronchial Coring Needles. These devices are for use in interventional bronchoscopic procedures for lung cancer and other diseases.

Bronchoscopists face numerous challenges in the accurate diagnosis and staging of lung diseases. One difficulty is finding an appropriate route through the lung airways to the area of concern. Planning involves the careful examination of CT (computed tomography) scans, during which the bronchoscopist mentally reconstructs the three dimensional airway tree from the two dimensional images for later recall during the procedure. Not surprisingly, studies have shown that once past the main airway branches there can be significant confusion about the bronchoscope’s location and the path to follow to reach the target area.[i] Once successfully reaching the desired location in the airway, a tissue sample is traditionally collected using a needle that pierces the airway wall (transbronchial needle aspiration or TBNA). However, TBNA many times does not acquire the intact cell samples that are required to discriminate malignant from benign disease and that are required for a successful bronchoscopic procedure.[ii],[iii] More importantly, many physicians are hesitant to even perform TBNA because of the risk of bleeding should they puncture a blood vessel on the other side of the airway. They instead send patients to undergo more invasive procedures such as mediastinoscopy or trans-thoracic needle aspiration.

The LungPoint system supports the physician in both preparation for a bronchoscopic procedure, with an imaging and 3D simulation program, and guidance during the actual procedure. The software uses the patient’s CT scan to provide a realistic rendering of the airways and automatically generates a path to the selected target location(s). During bronchoscopy it provides a side-by-side view of the planned path and the actual location of the bronchoscope to accurately reaching targets.

“Research shows that a large number of diagnostic bronchoscopies performed in the lung fail to reach designated targets, causing patients to endure repeat or additional procedures. There is clearly a strong clinical need for improved navigation in the lung,” states Cary Cole, CEO of Broncus Technologies. “It is our hope that this new system will meet that need and do so in a cost-effective manner.”

“The LungPoint system finally makes bronchoscopy planning and navigation sensible and straightforward”, states Rebecca Bascom, MD, MPH, and Professor of Medicine, Penn State University. “The capacity to quickly plan a procedure and create visual guidance to a lesion could result in a safer procedure and might decrease the need for more invasive surgeries.”

The LungPoint software can be used in combination with the Yield™ Mini Doppler System and the Yield™ Transbronchial Coring Needles. The first is a novel bronchoscopic ultrasound Doppler catheter that can detect blood flow behind the airway wall to help physicians avoid blood vessels during biopsy and other procedures. The needles are disposable, single-patient-use catheters and have unique coring tips to acquire samples for pathology. The handle includes actuation stops at 5 mm increments to control the needle penetration. All the Yield products incorporate proprietary flexible shafts to increase access to lung targets in previously hard-to-reach locations.

“We want to advance the field of bronchoscopy by giving physicians innovative new tools to extend their practice,” states Cary Cole. “We’ve been very pleased to see the enthusiastic reception to these product lines.”

The LungPoint system does not require any special fixtures or disposables and is based on new advanced image processing methods that were developed over a 10 year period. It runs on off-the-shelf PCs and can be configured with treatment planning and/or procedure navigation software. An early version of the virtual bronchoscopic navigation approach has previously been tested at Hershey Medical Center while the LungPoint system is beginning market evaluation at several prestigious hospitals in the US.


[i] Merritt SA, Gibbs JD, Yu KC, Patel V, Rai L, Cornish DC, Bascom R, Higgins WE. Image-guided bronchoscopy for peripheral lung lesions: a phantom study. Chest 2008 Nov;134(5):1017-26. Epub 2008 Jun 26.

[ii] Rivera MP and Mehta AC. Initial Diagnosis of Lung Cancer: ACCP Evidence-Based Clinical Practice Guidelines. Chest 2007;132: 131-148.

[iii] Patel NM, Pohlman A, Husain A, Noth I, Hall JB, Kress JP. Conventional Transbronchial Needle Aspiration Decreases the Rate of Surgical Sampling in Intrathoracic Lymphadenopathy. Chest 2007;131;773-778.

Broncus Technologies, Inc.